Interlinking at least two protein molecules via nucleic acid chains

Antibodies Co-Bodies

An oligonucleotide is attached to each protein and the linked, flexible molecule forms by hybridisation between chains.

Patent Filed 1995, application published 1996

Nucleic acids and other linkers had been used previously to join proteins to each other. The new method provides for ease of assembly and the product is a conjugate molecule in which the link between component proteins is flexible.